Metastatic Carcinoid Tumors and the Malignant Carcinoid Syndrome

A Case of Carcinoid Syndrome Due to Malignant Metastatic Carcinoid Tumor with Carcinoid Heart Disease Involving Four Cardiac Valves

BACKGROUND Carcinoid tumor, benign, low-grade malignant, and high-grade malignant, can be associated with the release of vasoactive substances that cause symptoms including cutaneous flushing, diarrhea, and bronchospasm. In 50-60% of patients with carcinoid syndrome, the vasoactive substances cause fibrosis of the pulmonary and tricuspid heart valves which lead to regurgitation and right-sided ...

Anesthesia and the malignant carcinoid syndrome.

Carcinoid tumors.

Carcinoid tumors are rare, slow-growing neuroendocrine neoplasms that often are indolent and may not become clinically apparent until there has been metastatic spread or evidence of carcinoid syndrome. Recent evidence has revealed that the overall incidence of carcinoid tumors has been steadily increasing, and although the disease was thought to be relatively benign, it is now considered one of...

MDCT imaging in malignant carcinoid syndrome.

A 65-year-old lady presented with sudden onset of palpitations, headache, perspirations and flushing. Clinical examination revealed tenderness in right lumbar region. Ultrasound abdomen revealed multiple hyperechoic hepatic lesions and a mesenteric mass. Contrast-enhanced computerized tomography (CECT) abdomen revealed multiple hypervascular hepatic lesions. Two enhancing mesenteric masses with...

Carcinoid syndrome due to a malignant somatostatinoma.

Somatostatinoma is one of the rarest tumours of the endocrine pancreas. Cardinal manifestations of a somatostatinoma include gallstones, mild diabetes mellitus, steatorrhoea, diarrhoea and dyspepsia. Like any other pancreatic islet cell carcinoma, a somatostatinoma may also produce several different hormones such as adrenocorticotropic hormone, calcitonin, vasoactive intestinal polypeptide, pan...